Big Data Use Cases - BioScience

Manage biomedicine Big Data coming from two sources:

• Genomics-driven end (genotyping, gene expression, and now next-generation sequencing data)
• Payer-provider end (electronic medical records, pharmacy prescription information, insurance records)

Perform next-generation genome sequencing

• Greatly simplifies the sequencing of DNA, generate whole genome sequences for large numbers of people at low cost
• Raw data-wise, is 4 terabytes of data from one person

Perform clinical trials using vast trove of observational healthcare data

• Analyze pharmacy and insurance claims data together to identify adverse drug events
• Delve into molecular-level data to discover biomarkers that help classify patients based on their response to existing treatments
• Push their results out to physicians